Perforation of tympanic membrane

DOID MESH PheWeb

H8_PERFORATION

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H72

Hospital discharge: ICD-9 3842

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H72

Cause of death: ICD-9 3842

Cause of death: ICD-8 $!$

2333

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2333

Check minimum number of events None

2333

Include endpoints None

2333

H8_PERFORATION

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H65-H75

Name in latin Perforatio membranae tympanicae

Similar endpoints

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List of similar endpoints to Perforation of tympanic membrane based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2219	1234	985
Unadjusted prevalence (%)	0.72	0.71	0.73
Mean age at first event (years)	48.01	45.99	50.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.76 [1.07, 2.89]	2.5e-2	184
15 years	0.01	1.30 [0.86, 1.95]	2.1e-1	94
5 years	0.00	2.28 [1.55, 3.36]	2.9e-5	47
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_PERFORATION – Perforation of tympanic membrane
GWS hits: 2

Survival analyses between endpoints

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Plot

before Perforation of tympanic membrane
after Perforation of tympanic membrane

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Table

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Drugs most likely to be purchased after Perforation of tympanic membrane

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