Disorders of vitreous body and globe

H7_VITREOUS

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H43-H45
Cause of death: ICD-10 H43-H45

11457

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

11457

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Check minimum number of events None

11457

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Include endpoints

11613

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H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Disorders of vitreous body and globe based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 11265 7095 4170
Unadjusted prevalence (%) 3.65 4.09 3.09
Mean age at first event (years) 61.57 61.03 62.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.75 [1.36, 2.24] 1.2e-5 741
15 years 0.01 1.06 [0.85, 1.32] 6.0e-1 375
5 years 0.00 1.95 [1.59, 2.39] 1.3e-10 236
1 year 0.00 2.70 [2.01, 3.64] 5.3e-11 62

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_VITREOUS – Disorders of vitreous body and globe
GWS hits: 1

Survival analyses between endpoints

Plot

before Disorders of vitreous body and globe
after Disorders of vitreous body and globe

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Drugs most likely to be purchased after Disorders of vitreous body and globe