Disorders of globe

H7_GLOBE

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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H7_GLOBE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 484 251 233
Unadjusted prevalence (%) 0.16 0.14 0.17
Mean age at first event (years) 56.90 56.98 56.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.54 [0.64, 3.70] 3.3e-1 107
15 years 0.01 1.15 [0.58, 2.28] 6.9e-1 54
5 years 0.00 1.82 [1.06, 3.13] 3.0e-2 31
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_GLOBE – Disorders of globe
GWS hits: 0

Survival analyses between endpoints

Plot

before Disorders of globe
after Disorders of globe

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Drugs most likely to be purchased after Disorders of globe