Disorders of vitreous body

H7_VITRBODYGLOBE

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H43

Cause of death: ICD-10 H43

11098

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

11098

Check minimum number of events None

11098

Include endpoints

H7_VITRPROLAPSE

H7_VITRHAEMORR

H7_VITRCRYSTAL

H7_VITROPACIT

H7_VITROTH

11187

H7_VITRBODYGLOBE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H43-H45

Name in latin Morbositates corporis vitrei

Similar endpoints

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List of similar endpoints to Disorders of vitreous body based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	10849	6880	3969
Unadjusted prevalence (%)	3.52	3.96	2.94
Mean age at first event (years)	61.76	61.15	62.80

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.61 [1.25, 2.08]	2.3e-4	648
15 years	0.01	1.05 [0.84, 1.32]	6.7e-1	328
5 years	0.00	2.22 [1.81, 2.72]	2.6e-14	210
1 year	0.00	2.78 [2.02, 3.82]	3.2e-10	50

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_VITRBODYGLOBE – Disorders of vitreous body
GWS hits: 2

Survival analyses between endpoints

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Plot

before Disorders of vitreous body
after Disorders of vitreous body

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Table

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Drugs most likely to be purchased after Disorders of vitreous body

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