Other and unspecified corneal deformities and disorders

H7_CORNEALNAS

corneal disease: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H18.7, H18.8, H18.9
Hospital discharge: ICD-9 371[7-9]
Hospital discharge: ICD-8 37860
Cause of death: ICD-10 H18.7, H18.8, H18.9
Cause of death: ICD-9 371[7-9]
Cause of death: ICD-8 37860

650

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

650

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Check minimum number of events None

650

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Include endpoints None

650

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H7_CORNEALNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 629 383 246
Unadjusted prevalence (%) 0.20 0.22 0.18
Mean age at first event (years) 49.93 49.22 51.03

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.26 [1.18, 4.31] 1.4e-2 35
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_CORNEALNAS – Other and unspecified corneal deformities and disorders
GWS hits: 3

Survival analyses between endpoints

Plot

before Other and unspecified corneal deformities and disorders
after Other and unspecified corneal deformities and disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified corneal deformities and disorders