Other and unspecified corneal deformities and disorders

H7_CORNEALNAS

corneal disease: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H18.7, H18.8, H18.9

Hospital discharge: ICD-9 371[7-9]

Hospital discharge: ICD-8 37860

Cause of death: ICD-10 H18.7, H18.8, H18.9

Cause of death: ICD-9 371[7-9]

Cause of death: ICD-8 37860

650

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

650

Check minimum number of events None

650

Include endpoints None

650

H7_CORNEALNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF6

Similar endpoints

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List of similar endpoints to Other and unspecified corneal deformities and disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	629	383	246
Unadjusted prevalence (%)	0.20	0.22	0.18
Mean age at first event (years)	49.93	49.22	51.03

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.26 [1.18, 4.31]	1.4e-2	35
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_CORNEALNAS – Other and unspecified corneal deformities and disorders
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other and unspecified corneal deformities and disorders
after Other and unspecified corneal deformities and disorders

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Other and unspecified corneal deformities and disorders

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