Other and unsepcified mononeuropathies, also in other diseases

G6_MONOOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G58.8, G58.9, G59*

Hospital discharge: ICD-9 3559

Hospital discharge: ICD-8 35708

Cause of death: ICD-10 G58.8, G58.9, G59*

Cause of death: ICD-9 3559

Cause of death: ICD-8 35708

713

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

708

Check minimum number of events None

708

Include endpoints None

708

G6_MONOOTHUNS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unsepcified mononeuropathies, also in other diseases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Diabetic mononeuropathy

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	688	375	313
Unadjusted prevalence (%)	0.22	0.22	0.23
Mean age at first event (years)	47.84	45.80	50.29

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.81 [0.97, 3.39]	6.2e-2	83
15 years	0.01	1.21 [0.71, 2.06]	4.9e-1	37
5 years	0.00	2.44 [1.45, 4.10]	7.6e-4	24
1 year	0.00	5.79 [2.89, 11.59]	7.0e-7	11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MONOOTHUNS – Other and unsepcified mononeuropathies, also in other diseases
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other and unsepcified mononeuropathies, also in other diseases
after Other and unsepcified mononeuropathies, also in other diseases

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Table

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Drugs most likely to be purchased after Other and unsepcified mononeuropathies, also in other diseases

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