Other and unspecified mononeuropathies of lower limb

G6_MONOLOWOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 G57.8, G57.9
Hospital discharge: ICD-9 355[7-8]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G57.8, G57.9
Cause of death: ICD-9 355[7-8]
Cause of death: ICD-8 $!$

628

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

628

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Check minimum number of events None

628

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Include endpoints None

628

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G6_MONOLOWOTHUNS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 606 435 171
Unadjusted prevalence (%) 0.20 0.25 0.13
Mean age at first event (years) 51.85 51.10 53.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.72 [0.38, 1.35] 3.1e-1 39
15 years 0.00 0.55 [0.28, 1.08] 8.2e-2 19
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MONOLOWOTHUNS – Other and unspecified mononeuropathies of lower limb
GWS hits: 0

Survival analyses between endpoints

Plot

before Other and unspecified mononeuropathies of lower limb
after Other and unspecified mononeuropathies of lower limb

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Drugs most likely to be purchased after Other and unspecified mononeuropathies of lower limb