Other and unspecified mononeuropathies of lower limb

G6_MONOLOWOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G57.8, G57.9

Hospital discharge: ICD-9 355[7-8]

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 G57.8, G57.9

Cause of death: ICD-9 355[7-8]

Cause of death: ICD-8 $!$

628

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

628

Check minimum number of events None

628

Include endpoints None

628

G6_MONOLOWOTHUNS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified mononeuropathies of lower limb based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	606	435	171
Unadjusted prevalence (%)	0.20	0.25	0.13
Mean age at first event (years)	51.85	51.10	53.74

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.72 [0.38, 1.35]	3.1e-1	39
15 years	0.00	0.55 [0.28, 1.08]	8.2e-2	19
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MONOLOWOTHUNS – Other and unspecified mononeuropathies of lower limb
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other and unspecified mononeuropathies of lower limb
after Other and unspecified mononeuropathies of lower limb

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Table

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Drugs most likely to be purchased after Other and unspecified mononeuropathies of lower limb

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