Other headache syndromes


acute chest syndrome: A vaso-occlusive crisis of the pulmonary vasculature occurring in patients with sickle cell disease. It is characterized by the presence of a new radiodensity on a chest radiograph accompanied by fever, cough, sputum production, dyspnea, or hypoxia.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 G44
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 34601
Cause of death: ICD-10 G44
Cause of death: ICD-9 $!$
Cause of death: ICD-8 34601


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Alia syndromata cephalalgica

Summary Statistics

Key figures

All Female Male
Number of individuals 12111 8897 3214
Unadjusted prevalence (%) 3.93 5.13 2.38
Mean age at first event (years) 48.58 47.50 51.57


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.57 [1.23, 2.02] 3.5e-4 501
15 years 0.01 1.07 [0.82, 1.39] 6.3e-1 270
5 years 0.00 1.46 [1.06, 2.01] 2.2e-2 107
1 year 0.00 3.51 [2.38, 5.17] 2.1e-10 47

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: G6_HEADACHE – Other headache syndromes
GWS hits: 0

Survival analyses between endpoints


before Other headache syndromes
after Other headache syndromes

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Drugs most likely to be purchased after Other headache syndromes