Toxic encephalopathy

G6_ENCEPHTOX

toxic encephalopathy: A group of neurologic disorders caused by damage to the nervous system following exposure to pharmacologic, biologic, and chemical agents. Examples of neurotoxins include chemotherapy agents, radiation treatment, heavy metals, pesticides, and food additives.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G92

Hospital discharge: ICD-9 3498B

Hospital discharge: ICD-8 32302

Cause of death: ICD-10 G92

Cause of death: ICD-9 3498B

Cause of death: ICD-8 32302

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

G6_ENCEPHTOX

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G90-G99

Name in latin Encephalopathia toxica

Similar endpoints

↥

List of similar endpoints to Toxic encephalopathy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	49	9	40
Unadjusted prevalence (%)	0.02	0.01	0.03
Mean age at first event (years)	54.68	50.20	55.69

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: G6_ENCEPHTOX – Toxic encephalopathy
GWS hits:

Survival analyses between endpoints

↥

Plot

before Toxic encephalopathy
after Toxic encephalopathy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Toxic encephalopathy

↥