Causalgia

G6_CAUSALGIA

causalgia: Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia , not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G56.4

Hospital discharge: ICD-9 3544

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 G56.4

Cause of death: ICD-9 3544

Cause of death: ICD-8 $!$

342

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

342

Check minimum number of events None

342

Include endpoints None

342

G6_CAUSALGIA

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G56

Name in latin Causalgia

Similar endpoints

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List of similar endpoints to Causalgia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	329	237	92
Unadjusted prevalence (%)	0.11	0.14	0.07
Mean age at first event (years)	46.09	45.93	46.48

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_CAUSALGIA – Causalgia
GWS hits: 1

Survival analyses between endpoints

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Plot

before Causalgia
after Causalgia

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Causalgia

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