Moderate mental retardation

F5_MODRET

mental retardation: ['Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F71

Hospital discharge: ICD-9 3180

Hospital discharge: ICD-8 312

Cause of death: ICD-10 F71

Cause of death: ICD-9 3180

Cause of death: ICD-8 312

214

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

149

Check minimum number of events None

149

Include endpoints None

149

F5_MODRET

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F70-F79

Name in latin Retardatio mentalis moderata

Similar endpoints

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List of similar endpoints to Moderate mental retardation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	141	66	75
Unadjusted prevalence (%)	0.05	0.04	0.06
Mean age at first event (years)	27.67	26.12	29.04

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_MODRET – Moderate mental retardation
GWS hits: 0

Survival analyses between endpoints

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Plot

before Moderate mental retardation
after Moderate mental retardation

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Table

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Drugs most likely to be purchased after Moderate mental retardation

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