Mental and behavioural disorders due to alcohol

F5_ALCOHOL

psychosis: An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F10
Hospital discharge: ICD-9 303|291
Hospital discharge: ICD-8 291
Hospital discharge: excluded ICD-10 F10.0
Cause of death: ICD-10 F10
Cause of death: ICD-9 303|291
Cause of death: ICD-8 291
Cause of death: excluded ICD-10 F10.1

14560

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13598

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Check minimum number of events None

13598

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Include endpoints

16558

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F5_ALCOHOL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu alcohol

Similar endpoints

List of similar endpoints to Mental and behavioural disorders due to alcohol based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 16077 5168 10909
Unadjusted prevalence (%) 5.21 2.98 8.08
Mean age at first event (years) 44.80 40.59 46.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 5.26 [4.42, 6.26] 3.2e-78 2895
15 years 0.01 3.08 [2.65, 3.57] 1.4e-49 1156
5 years 0.00 5.29 [4.65, 6.03] <1e-100 634
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_ALCOHOL – Mental and behavioural disorders due to alcohol
GWS hits: 4

Survival analyses between endpoints

Plot

before Mental and behavioural disorders due to alcohol
after Mental and behavioural disorders due to alcohol

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Drugs most likely to be purchased after Mental and behavioural disorders due to alcohol