Acute alcohol intoxication

ALCOHOLACUTE10

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F10.0

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 F10.0

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

4970

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4970

Check minimum number of events None

4970

Include endpoints None

4970

ALCOHOLACUTE10

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F10

Similar endpoints

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List of similar endpoints to Acute alcohol intoxication based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4820	1668	3152
Unadjusted prevalence (%)	1.56	0.96	2.33
Mean age at first event (years)	48.57	42.26	51.91

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.16	14.42 [10.91, 19.07]	3.2e-78	945
15 years	0.02	3.88 [2.88, 5.22]	4.2e-19	209
5 years	0.01	9.31 [7.17, 12.10]	1.0e-62	197
1 year	0.02	103.85 [83.47, 129.20]	<1e-100	510

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ALCOHOLACUTE10 – Acute alcohol intoxication
GWS hits: 1

Survival analyses between endpoints

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Plot

before Acute alcohol intoxication
after Acute alcohol intoxication

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Table

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Drugs most likely to be purchased after Acute alcohol intoxication

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