Testicular hypofunction

E4_TESTICHYPO

testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only males

140728

Check conditions None

140728

Filter registries

Hospital Discharge: ICD-10 E29.1#

Hospital discharge: ICD-9 257[1-2]

Hospital discharge: ICD-8 2571

Cause of death: ICD-10 E29.1#

Cause of death: ICD-9 257[1-2]

Cause of death: ICD-8 2571

KELA reimbursements: KELA codes ANY

KELA reimbursements: ICD-10 E29.1#

76591

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

408

Check minimum number of events None

408

Include endpoints None

408

E4_TESTICHYPO

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E29

Name in latin Hypofunctio testium

Similar endpoints

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List of similar endpoints to Testicular hypofunction based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Testicular hypofunction, drug-induced

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	396	-	396
Unadjusted prevalence (%)	0.13	-	0.29
Mean age at first event (years)	49.22	-	49.22

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.12	8.96 [4.00, 20.12]	1.0e-7	16
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_TESTICHYPO – Testicular hypofunction
GWS hits: 0

Survival analyses between endpoints

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Plot

before Testicular hypofunction
after Testicular hypofunction

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Testicular hypofunction

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