Nutritional marasmus

E4_MARASMUS

marasmus: The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E41

Hospital discharge: ICD-9 261

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E41

Cause of death: ICD-9 261

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

E4_MARASMUS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E40-E46

Name in latin Malnutritio gravis ex deficientia energetica (marasmus nutritionalis)

Similar endpoints

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List of similar endpoints to Nutritional marasmus based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	24	12	12
Unadjusted prevalence (%)	0.01	0.01	0.01
Mean age at first event (years)	47.94	46.95	48.92

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_MARASMUS – Nutritional marasmus
GWS hits:

Survival analyses between endpoints

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Plot

before Nutritional marasmus
after Nutritional marasmus

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Table

Loading survival analyses table

Drugs most likely to be purchased after Nutritional marasmus

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