Kwashiorkor

E4_KWASHIORKOR

kwashiorkor: A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning 'displaced child'. Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed)

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E40

Hospital discharge: ICD-9 260

Hospital discharge: ICD-8 268

Cause of death: ICD-10 E40

Cause of death: ICD-9 260

Cause of death: ICD-8 268

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

E4_KWASHIORKOR

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E40-E46

Name in latin Malnutritio gravis ex deficientia proteinica

Similar endpoints

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List of similar endpoints to Kwashiorkor based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	29	13	16
Unadjusted prevalence (%)	0.01	0.01	0.01
Mean age at first event (years)	38.64	28.24	47.09

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_KWASHIORKOR – Kwashiorkor
GWS hits:

Survival analyses between endpoints

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Plot

before Kwashiorkor
after Kwashiorkor

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Table

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Drugs most likely to be purchased after Kwashiorkor

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