Drug-induced neutropenia

PheWeb

DRUGADVERS_NEUTROPENIA

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D70.82#

1564

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10

1564

Check minimum number of events None

1564

Include endpoints None

1564

DRUGADVERS_NEUTROPENIA

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Drug-induced neutropenia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1521	996	525
Unadjusted prevalence (%)	0.49	0.57	0.39
Mean age at first event (years)	58.81	57.29	61.70

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.22	19.77 [11.53, 33.89]	2.0e-27	261
15 years	0.01	2.10 [1.11, 3.98]	2.3e-2	27
5 years	0.01	11.40 [7.25, 17.93]	6.5e-26	82
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DRUGADVERS_NEUTROPENIA – Drug-induced neutropenia
GWS hits: 1

Survival analyses between endpoints

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Plot

before Drug-induced neutropenia
after Drug-induced neutropenia

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Table

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Drugs most likely to be purchased after Drug-induced neutropenia

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