Agranulocytosis

DOID MESH PheWeb

D3_AGRANULOCYTOSIS

No definition available.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D70

Hospital discharge: ICD-9 2880

Hospital discharge: ICD-8 2889

Cause of death: ICD-10 D70

Cause of death: ICD-9 2880

Cause of death: ICD-8 2889

2569

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2562

Check minimum number of events None

2562

Include endpoints None

2562

D3_AGRANULOCYTOSIS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D70-D77

Name in latin Agranulocytosis

Similar endpoints

↥

List of similar endpoints to Agranulocytosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Drug-induced neutropenia

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	2491	1614	877
Unadjusted prevalence (%)	0.81	0.93	0.65
Mean age at first event (years)	56.30	54.70	59.26

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.19	16.44 [11.26, 23.99]	9.3e-48	394
15 years	0.01	2.41 [1.62, 3.60]	1.4e-5	49
5 years	0.01	12.26 [8.73, 17.22]	2.0e-47	129
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: D3_AGRANULOCYTOSIS – Agranulocytosis
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Agranulocytosis
after Agranulocytosis

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Agranulocytosis

↥