Dipeptidyl peptidase 4 (DPP-4) inhibitors

PheWeb

DPP4INH

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC A10BG

3476

Check pre-conditions, main-only, mode, ICD version None

2684

Check minimum number of events

Min. number of events 3

2684

Include endpoints None

2684

DPP4INH

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Dipeptidyl peptidase 4 (DPP-4) inhibitors based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2604	1077	1527
Unadjusted prevalence (%)	0.84	0.62	1.13
Mean age at first event (years)	59.85	58.91	60.50

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.00 [1.37, 2.91]	3.2e-4	326
15 years	0.01	1.59 [1.09, 2.30]	1.5e-2	236
5 years	0.00	2.11 [1.50, 2.95]	1.4e-5	79
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DPP4INH – Dipeptidyl peptidase 4 (DPP-4) inhibitors
GWS hits:

Survival analyses between endpoints

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Plot

before Dipeptidyl peptidase 4 (DPP-4) inhibitors
after Dipeptidyl peptidase 4 (DPP-4) inhibitors

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Table

Loading survival analyses table

Drugs most likely to be purchased after Dipeptidyl peptidase 4 (DPP-4) inhibitors

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