Unspecified diabetic retinopathy

DM_RETINA_NOS

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

DM_EYE_OPER

5092

Filter registries

Hospital Discharge: ICD-10 H3609|E1.7|E1.3

Hospital discharge: ICD-9 3620A|2504

Hospital discharge: ICD-8 25002

Hospital discharge: excluded ICD-10 E12.3+

Cause of death: ICD-10 H3609|E1.7|E1.3

Cause of death: ICD-9 3620A|2504

Cause of death: ICD-8 25002

Cause of death: excluded ICD-10 E12.3+

2783

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2783

Check minimum number of events None

2783

Include endpoints None

2783

DM_RETINA_NOS

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Unspecified diabetic retinopathy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Proliferative diabetic retinopathy (Unspecified diabetic retinopathy + operation)

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2719	1091	1628
Unadjusted prevalence (%)	0.88	0.63	1.21
Mean age at first event (years)	47.86	46.34	48.88

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.65 [2.62, 5.07]	1.3e-14	402
15 years	0.01	2.22 [1.57, 3.15]	7.7e-6	199
5 years	0.00	2.90 [2.07, 4.05]	5.4e-10	84
1 year	0.00	5.36 [3.43, 8.39]	1.8e-13	29

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_RETINA_NOS – Unspecified diabetic retinopathy
GWS hits: 9

Survival analyses between endpoints

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Plot

before Unspecified diabetic retinopathy
after Unspecified diabetic retinopathy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Unspecified diabetic retinopathy

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