Neovascular glaucoma

DM_NEOVASCULAR_GLAUCOMA

neovascular glaucoma: Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uvietis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H40.5

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H40.5

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

880

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

880

Check minimum number of events None

880

Include endpoints None

880

DM_NEOVASCULAR_GLAUCOMA

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H40

Name in latin Glaucoma [secundarium] post aliam morbositatem oculi

Similar endpoints

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List of similar endpoints to Neovascular glaucoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	841	384	457
Unadjusted prevalence (%)	0.27	0.22	0.34
Mean age at first event (years)	60.15	57.19	62.63

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.19 [1.70, 5.99]	3.2e-4	166
15 years	0.01	1.53 [0.89, 2.62]	1.2e-1	67
5 years	0.00	3.49 [2.31, 5.28]	2.7e-9	69
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_NEOVASCULAR_GLAUCOMA – Neovascular glaucoma
GWS hits: 0

Survival analyses between endpoints

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Plot

before Neovascular glaucoma
after Neovascular glaucoma

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Neovascular glaucoma

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