Secondary polycythaemia

D3_SCNDPOLYCYTHAEMIA

polycythemia: Abnormally high mass or concentration of red blood cells in the blood, either due to an increase in erythropoiesis or a decrease in plasma volume.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D75.1

Hospital discharge: ICD-9 2890

Hospital discharge: ICD-8 28900

Cause of death: ICD-10 D75.1

Cause of death: ICD-9 2890

Cause of death: ICD-8 28900

417

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

417

Check minimum number of events None

417

Include endpoints None

417

D3_SCNDPOLYCYTHAEMIA

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D75

Name in latin Polycythaemia secundaria

Similar endpoints

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List of similar endpoints to Secondary polycythaemia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	407	141	266
Unadjusted prevalence (%)	0.13	0.08	0.20
Mean age at first event (years)	55.89	54.98	56.37

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_SCNDPOLYCYTHAEMIA – Secondary polycythaemia
GWS hits: 2

Survival analyses between endpoints

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Plot

before Secondary polycythaemia
after Secondary polycythaemia

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Secondary polycythaemia

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