Oher diseases of blood and blood-forming organs

DOID EFO MESH SNOMED PheWeb

D3_OTHERBLOOD

hematologic disease: A disease involving the hematopoietic system.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D75

Cause of death: ICD-10 D75

1256

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1256

Check minimum number of events None

1256

Include endpoints

D3_FAMIERYTHROCYTOCIS

D3_SCNDPOLYCYTHAEMIA

D3_BLOODNAS

1346

D3_OTHERBLOOD

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D70-D77

Name in latin Alii morbi sanguinis et organorum haematopoeticorum

Similar endpoints

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List of similar endpoints to Oher diseases of blood and blood-forming organs based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1312	645	667
Unadjusted prevalence (%)	0.43	0.37	0.49
Mean age at first event (years)	56.55	55.20	57.85

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.04 [1.93, 4.77]	1.5e-6	189
15 years	0.01	1.59 [0.97, 2.60]	6.6e-2	88
5 years	0.00	2.56 [1.57, 4.18]	1.6e-4	57
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_OTHERBLOOD – Oher diseases of blood and blood-forming organs
GWS hits: 2

Survival analyses between endpoints

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Plot

before Oher diseases of blood and blood-forming organs
after Oher diseases of blood and blood-forming organs

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Table

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Drugs most likely to be purchased after Oher diseases of blood and blood-forming organs

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