Immunodeficiency with predominantly antibody defects

DOID MESH PheWeb

D3_IMMUDEFANTIBODY

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D80

Cause of death: ICD-10 D80

560

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

560

Check minimum number of events None

560

Include endpoints

D3_HEREDHYPOGAMMA

D3_NONHEREDHYPOGAMMA

D3_DEF_IIGA

D3_DEF_IGG

D3_DEF_IGM

D3_IMMUDEF_INCR_IGM

D3_AB_DEF_NORMHYPERIG

D3_TRANSHYPOGAMMAINFANT

D3_IMMUDEFANTIBODYNAS

576

D3_IMMUDEFANTIBODY

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D80-D89

Name in latin Deficientia immunalis praecipue cum vitiis anticorporum

Similar endpoints

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List of similar endpoints to Immunodeficiency with predominantly antibody defects based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	553	366	187
Unadjusted prevalence (%)	0.18	0.21	0.14
Mean age at first event (years)	45.98	45.71	46.51

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	5.04 [1.95, 13.07]	8.6e-4	40
15 years	0.01	2.07 [0.75, 5.70]	1.6e-1	14
5 years	0.01	6.99 [2.95, 16.59]	1.0e-5	16
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_IMMUDEFANTIBODY – Immunodeficiency with predominantly antibody defects
GWS hits: 2

Survival analyses between endpoints

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Plot

before Immunodeficiency with predominantly antibody defects
after Immunodeficiency with predominantly antibody defects

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Table

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Drugs most likely to be purchased after Immunodeficiency with predominantly antibody defects

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