Other coagulation defects


thrombophilia: A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 D68
Cause of death: ICD-10 D68


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D65-D69
Name in latin Aliae defectus coagulationis

Similar endpoints

List of similar endpoints to Other coagulation defects based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1430 964 466
Unadjusted prevalence (%) 0.46 0.56 0.35
Mean age at first event (years) 48.97 44.93 57.33


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.68 [2.27, 9.65] 2.9e-5 187
15 years 0.01 0.90 [0.42, 1.92] 7.9e-1 29
5 years 0.00 2.25 [1.12, 4.50] 2.3e-2 25
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: D3_COAGOTHER – Other coagulation defects
GWS hits: 10

Survival analyses between endpoints


before Other coagulation defects
after Other coagulation defects

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Drugs most likely to be purchased after Other coagulation defects