Other and unspecified coagulation defects

D3_COAGDEFNAS

blood coagulation disease: A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D68.8, D68.9

Hospital discharge: ICD-9 2869

Hospital discharge: ICD-8 2869

Cause of death: ICD-10 D68.8, D68.9

Cause of death: ICD-9 2869

Cause of death: ICD-8 2869

941

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

941

Check minimum number of events None

941

Include endpoints None

941

D3_COAGDEFNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified coagulation defects based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	904	628	276
Unadjusted prevalence (%)	0.29	0.36	0.20
Mean age at first event (years)	47.39	44.60	53.73

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.49 [2.04, 9.87]	1.9e-4	54
15 years	0.01	1.66 [0.75, 3.68]	2.1e-1	17
5 years	0.00	3.07 [1.27, 7.41]	1.3e-2	17
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_COAGDEFNAS – Other and unspecified coagulation defects
GWS hits: 8

Survival analyses between endpoints

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Plot

before Other and unspecified coagulation defects
after Other and unspecified coagulation defects

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Other and unspecified coagulation defects

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