CR(E)ST syndrome

DOID MESH PheWeb

CREST

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M34.1

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M34.1

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

286

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

286

Check minimum number of events None

286

Include endpoints None

286

CREST

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M34

Name in latin Syndroma CREST

Similar endpoints

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List of similar endpoints to CR(E)ST syndrome based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	279	248	31
Unadjusted prevalence (%)	0.09	0.14	0.02
Mean age at first event (years)	56.32	56.27	56.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CREST – CR(E)ST syndrome
GWS hits: 1

Survival analyses between endpoints

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Plot

before CR(E)ST syndrome
after CR(E)ST syndrome

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Table

Loading survival analyses table

Drugs most likely to be purchased after CR(E)ST syndrome

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