Colorectal cancer

C3_COLORECTAL

colorectal cancer: A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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C3_COLORECTAL

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 4957 2096 2861
Unadjusted prevalence (%) 1.61 1.21 2.12
Mean age at first event (years) 66.26 64.29 67.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.80 [1.97, 3.98] 9.1e-9 1271
15 years 0.00 0.83 [0.55, 1.25] 3.7e-1 320
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_COLORECTAL – Colorectal cancer
GWS hits: 6

Survival analyses between endpoints

Plot

before Colorectal cancer
after Colorectal cancer

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Drugs most likely to be purchased after Colorectal cancer