Alcohol use disorder, ICD-based

PheWeb

AUD

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F10.1, F10.2

Hospital discharge: ICD-9 303

Hospital discharge: ICD-8 303

Cause of death: ICD-10 F10.1, F10.2

Cause of death: ICD-9 303

Cause of death: ICD-8 303

13026

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13026

Check minimum number of events None

13026

Include endpoints None

13026

AUD

Extra metadata

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Alcohol use disorder, ICD-based based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Alcohol dependence

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	12662	4004	8658
Unadjusted prevalence (%)	4.10	2.31	6.41
Mean age at first event (years)	44.27	40.87	45.84

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.64 [3.66, 5.88]	7.5e-37	2177
15 years	0.02	3.01 [2.48, 3.65]	3.9e-29	946
5 years	0.00	5.12 [4.23, 6.19]	3.4e-63	516
1 year	0.00	16.78 [13.75, 20.48]	<1e-100	338

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AUD – Alcohol use disorder, ICD-based
GWS hits: 6

Survival analyses between endpoints

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Plot

before Alcohol use disorder, ICD-based
after Alcohol use disorder, ICD-based

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Table

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Drugs most likely to be purchased after Alcohol use disorder, ICD-based

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