Allergic asthma (mode)


asthma: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 J45.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 J45.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Check mode of ICD-10 codes: %J450
Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 10877 7257 3620
Unadjusted prevalence (%) 3.53 4.18 2.68
Mean age at first event (years) 40.97 40.30 42.30


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.39 [1.89, 3.03] 4.8e-13 648
15 years 0.01 1.51 [1.22, 1.86] 1.7e-4 297
5 years 0.00 2.97 [2.41, 3.67] 4.0e-24 182
1 year 0.00 6.50 [4.90, 8.61] 1.1e-38 79

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: ALLERG_ASTHMA – Allergic asthma (mode)
GWS hits: 11

Survival analyses between endpoints


before Allergic asthma (mode)
after Allergic asthma (mode)

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Drugs most likely to be purchased after Allergic asthma (mode)