Wegener granulomatosis

M13_WEGENER

Granulomatosis with Polyangiitis: A small-vessel necrotizing vasculitis characterised by the association of inflammation of the vessel wall and peri- and extravascular granulomatosis.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M31.3

Hospital discharge: ICD-9 4464

Hospital discharge: ICD-8 4462

Cause of death: ICD-10 M31.3

Cause of death: ICD-9 4464

Cause of death: ICD-8 4462

380

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

362

Check minimum number of events None

362

Include endpoints None

362

M13_WEGENER

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M31

Name in latin Granulomatosis Wegener

Similar endpoints

↥

List of similar endpoints to Wegener granulomatosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	350	182	168
Unadjusted prevalence (%)	0.11	0.10	0.12
Mean age at first event (years)	52.98	51.65	54.43

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_WEGENER – Wegener granulomatosis
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Wegener granulomatosis
after Wegener granulomatosis

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Wegener granulomatosis

↥