Chronic gastritis

K11_CHRONGASTR

atrophic gastritis: GASTRITIS with atrophy of the GASTRIC MUCOSA, the GASTRIC PARIETAL CELLS, and the mucosal glands leading to ACHLORHYDRIA. Atrophic gastritis usually progresses from chronic gastritis.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K29.3, K29.4, K29.5
Hospital discharge: ICD-9 5351|5354
Hospital discharge: ICD-8 53503
Cause of death: ICD-10 K29.3, K29.4, K29.5
Cause of death: ICD-9 5351|5354
Cause of death: ICD-8 53503

7902

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7902

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Check minimum number of events None

7902

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Include endpoints None

7902

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K11_CHRONGASTR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 7605 4321 3284
Unadjusted prevalence (%) 2.46 2.49 2.43
Mean age at first event (years) 60.12 58.38 62.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.48 [2.05, 3.00] 1.6e-20 1134
15 years 0.01 1.44 [1.19, 1.74] 1.8e-4 546
5 years 0.00 2.67 [2.25, 3.16] 1.2e-29 342
1 year 0.00 5.03 [4.03, 6.28] 3.4e-46 128

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_CHRONGASTR – Chronic gastritis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Chronic gastritis
after Chronic gastritis

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Drugs most likely to be purchased after Chronic gastritis

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