Primary open-angle glaucoma

DOID MESH PheWeb

H7_GLAUCPRIMOPEN

No definition available.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H40.1

Hospital discharge: ICD-9 3651

Hospital discharge: ICD-8 3751[0-3]

Hospital discharge: excluded ICD-8 37511

Cause of death: ICD-10 H40.1

Cause of death: ICD-9 3651

Cause of death: ICD-8 3751[0-3]

Cause of death: excluded ICD-8 37511

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints

H7_GLAUCOMA_POAG

H7_GLAUCOMA_XFG

H7_GLAUCOMA_NTG

7209

H7_GLAUCPRIMOPEN

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H40

Name in latin Glaucoma simplex primarium

Similar endpoints

↥

List of similar endpoints to Primary open-angle glaucoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	6969	3853	3116
Unadjusted prevalence (%)	2.26	2.22	2.31
Mean age at first event (years)	67.38	67.21	67.59

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.41 [1.11, 1.78]	4.2e-3	1094
15 years	0.01	1.00 [0.83, 1.20]	9.9e-1	596
5 years	0.00	1.34 [1.13, 1.59]	9.9e-4	275
1 year	0.00	1.98 [1.52, 2.57]	3.9e-7	78

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: H7_GLAUCPRIMOPEN – Primary open-angle glaucoma
GWS hits: 16

Survival analyses between endpoints

↥

Plot

before Primary open-angle glaucoma
after Primary open-angle glaucoma

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Primary open-angle glaucoma

↥