Glaucoma, exfoliation

H7_GLAUCOMA_XFG

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H40.10
Hospital discharge: ICD-9 3651B
Hospital discharge: ICD-8 37512
Cause of death: ICD-10 H40.10
Cause of death: ICD-9 3651B
Cause of death: ICD-8 37512

2424

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2424

diagram downward connector

Check minimum number of events None

2424

diagram downward connector

Include endpoints None

2424

diagram downward connector
H7_GLAUCOMA_XFG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 H401
Name in latin Glaucoma capsulare [primarium/residuale] cum syndromate exfoliationis

Summary Statistics

Key figures

All Female Male
Number of individuals 2314 1331 983
Unadjusted prevalence (%) 0.75 0.77 0.73
Mean age at first event (years) 70.63 70.36 70.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.97 [0.61, 1.55] 9.1e-1 474
15 years 0.00 0.77 [0.54, 1.10] 1.5e-1 275
5 years 0.00 1.12 [0.84, 1.49] 4.6e-1 118
1 year 0.00 1.56 [1.03, 2.36] 3.7e-2 31

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_GLAUCOMA_XFG – Glaucoma, exfoliation
GWS hits: 2

Survival analyses between endpoints

Plot

before Glaucoma, exfoliation
after Glaucoma, exfoliation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Glaucoma, exfoliation