Gout, strict definition

DOID EFO MESH SNOMED PheWeb

GOUT_STRICT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

GOUT_IDIOP_NOS

4918

Filter registries

Medicine purchases: ATC M04AA01|M04AA03|M04AB01|M04AB03

3957

Check pre-conditions, main-only, mode, ICD version None

3399

Check minimum number of events

Min. number of events 3

3399

Include endpoints None

3399

GOUT_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Gout, strict definition based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3290	649	2641
Unadjusted prevalence (%)	1.07	0.37	1.96
Mean age at first event (years)	62.08	65.35	61.27

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.78 [1.29, 2.46]	4.9e-4	695
15 years	0.01	1.30 [0.97, 1.73]	7.6e-2	378
5 years	0.00	1.97 [1.51, 2.57]	4.7e-7	183
1 year	0.00	1.23 [0.76, 1.99]	3.9e-1	22

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: GOUT_STRICT – Gout, strict definition
GWS hits: 6

Survival analyses between endpoints

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Plot

before Gout, strict definition
after Gout, strict definition

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Table

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Drugs most likely to be purchased after Gout, strict definition

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