Brachial plexus disorders

G6_BRACHPLE

brachial plexus neuropathy: Diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the BRACHIAL PLEXUS. Clinical manifestations include regional pain, PARESTHESIA; MUSCLE WEAKNESS, and decreased sensation (HYPESTHESIA) in the upper extremity. These disorders may be associated with trauma (including BIRTH INJURIES); THORACIC OUTLET SYNDROME; NEOPLASMS; NEURITIS; RADIOTHERAPY; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp1351-2)

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G54.0

Hospital discharge: ICD-9 3530

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 G54.0

Cause of death: ICD-9 3530

Cause of death: ICD-8 $!$

2160

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2147

Check minimum number of events None

2147

Include endpoints None

2147

G6_BRACHPLE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G54

Name in latin Morbositates plexus brachialis

Similar endpoints

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List of similar endpoints to Brachial plexus disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2079	1501	578
Unadjusted prevalence (%)	0.67	0.87	0.43
Mean age at first event (years)	45.09	43.77	48.51

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.34 [1.36, 4.05]	2.3e-3	57
15 years	0.01	1.48 [0.82, 2.67]	2.0e-1	25
5 years	0.00	3.52 [1.76, 7.04]	3.6e-4	16
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_BRACHPLE – Brachial plexus disorders
GWS hits: 0

Survival analyses between endpoints

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Plot

before Brachial plexus disorders
after Brachial plexus disorders

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Table

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Drugs most likely to be purchased after Brachial plexus disorders

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