Use of memantine

PheWeb

ADMED_MEMANTINE

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC N06DX01

5350

Check pre-conditions, main-only, mode, ICD version None

4445

Check minimum number of events

Min. number of events 3

4445

Include endpoints None

4445

ADMED_MEMANTINE

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Use of memantine based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Use of other anti-dementia drugs

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4274	1981	2293
Unadjusted prevalence (%)	1.39	1.14	1.70
Mean age at first event (years)	79.53	79.72	79.37

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.09	7.44 [5.89, 9.40]	7.3e-64	1617
15 years	0.01	1.93 [1.54, 2.44]	2.0e-8	396
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ADMED_MEMANTINE – Use of memantine
GWS hits:

Survival analyses between endpoints

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Plot

before Use of memantine
after Use of memantine

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Use of memantine

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