Spondyloarthritis

PheWeb

SPONDYLOARTHRITIS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M45, M45+H22.1, M45+J99.8, M46

Hospital discharge: ICD-9 720

Hospital discharge: ICD-8 7124|7131|72699

Cause of death: ICD-10 M45, M45+H22.1, M45+J99.8, M46

Cause of death: ICD-9 720

Cause of death: ICD-8 7124|7131|72699

5188

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5017

Check minimum number of events None

5017

Include endpoints None

5017

SPONDYLOARTHRITIS

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Spondyloarthritis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4855	2458	2397
Unadjusted prevalence (%)	1.57	1.42	1.78
Mean age at first event (years)	45.36	43.98	46.77

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.64 [1.29, 2.08]	6.0e-5	619
15 years	0.01	1.14 [0.95, 1.38]	1.6e-1	313
5 years	0.00	1.46 [1.19, 1.81]	3.7e-4	121
1 year	0.00	3.08 [2.25, 4.23]	2.7e-12	49

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: SPONDYLOARTHRITIS – Spondyloarthritis
GWS hits: 15

Survival analyses between endpoints

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Plot

before Spondyloarthritis
after Spondyloarthritis

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Table

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Drugs most likely to be purchased after Spondyloarthritis

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