Opioids

RX_OPIOIDS

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Medicine purchases: ATC N02A

170988

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Check pre-conditions, main-only, mode, ICD version None

80008

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Check minimum number of events

Min. number of events 3

80008

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RX_OPIOIDS

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 77441 43357 34084
Unadjusted prevalence (%) 25.10 24.99 25.24
Mean age at first event (years) 53.78 52.05 55.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.58 [2.35, 2.84] 7.6e-86 8610
15 years 0.01 1.39 [1.27, 1.53] 4.8e-12 3442
5 years 0.00 3.27 [3.01, 3.56] <1e-100 2507
1 year 0.00 11.36 [10.16, 12.69] <1e-100 1707

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_OPIOIDS – Opioids
GWS hits:

Survival analyses between endpoints

Plot

before Opioids
after Opioids

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