Codeine or tramadol medication

RX_CODEINE_TRAMADOL

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Medicine purchases: ATC N02A02|N02AJ0|N02AJ1[3-5]|N02AA59|N02AA79

131190

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Check pre-conditions, main-only, mode, ICD version None

45838

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Check minimum number of events

Min. number of events 3

45838

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Include endpoints None

45838

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RX_CODEINE_TRAMADOL

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 44453 26088 18365
Unadjusted prevalence (%) 14.41 15.03 13.60
Mean age at first event (years) 54.73 53.06 57.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.71 [2.36, 3.10] 9.0e-47 2404
15 years 0.01 1.35 [1.17, 1.56] 3.6e-5 1169
5 years 0.00 3.06 [2.70, 3.47] 3.5e-68 1039
1 year 0.00 3.08 [2.55, 3.71] 1.3e-31 195

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_CODEINE_TRAMADOL – Codeine or tramadol medication
GWS hits: 2

Survival analyses between endpoints

Plot

before Codeine or tramadol medication
after Codeine or tramadol medication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Codeine or tramadol medication