First line medication for Crohns disease

PheWeb

RX_CROHN_1STLINE

No definition available.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC A07EC|H02AB

124635

Check pre-conditions, main-only, mode, ICD version None

61408

Check minimum number of events

Min. number of events 3

61408

Include endpoints None

61408

RX_CROHN_1STLINE

Extra metadata

First used in FinnGen datafreeze DF5

Similar endpoints

↥

List of similar endpoints to First line medication for Crohns disease based on the number of shared cases.

Broader endpoints:

Any prescribed medicine buy

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	59555	35539	24016
Unadjusted prevalence (%)	19.30	20.48	17.79
Mean age at first event (years)	51.05	48.38	54.99

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.38 [2.17, 2.62]	2.7e-71	6875
15 years	0.01	1.47 [1.35, 1.61]	3.8e-17	2982
5 years	0.00	3.19 [2.94, 3.46]	<1e-100	2040
1 year	0.00	5.53 [4.88, 6.26]	<1e-100	711

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: RX_CROHN_1STLINE – First line medication for Crohns disease
GWS hits: 12

Survival analyses between endpoints

↥

Plot

before First line medication for Crohns disease
after First line medication for Crohns disease

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after First line medication for Crohns disease

↥