ILD medications: prednisolone, methylprednisolone, prednisone

PheWeb

ILD_CORTISONE

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC H02AB0[6-7]|H02AB04

112655

Check pre-conditions, main-only, mode, ICD version None

51442

Check minimum number of events

Min. number of events 3

51442

Include endpoints None

51442

ILD_CORTISONE

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to ILD medications: prednisolone, methylprednisolone, prednisone based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Oral corticosteroids

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	49921	29901	20020
Unadjusted prevalence (%)	16.18	17.23	14.83
Mean age at first event (years)	51.70	48.80	56.04

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	2.02 [1.82, 2.24]	1.9e-40	5486
15 years	0.01	1.37 [1.25, 1.50]	2.7e-11	2598
5 years	0.00	2.58 [2.36, 2.81]	6.5e-100	1525
1 year	0.00	3.43 [2.98, 3.95]	1.4e-66	403

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ILD_CORTISONE – ILD medications: prednisolone, methylprednisolone, prednisone
GWS hits:

Survival analyses between endpoints

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Plot

before ILD medications: prednisolone, methylprednisolone, prednisone
after ILD medications: prednisolone, methylprednisolone, prednisone

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Table

Loading survival analyses table

Drugs most likely to be purchased after ILD medications: prednisolone, methylprednisolone, prednisone

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