Other specified congenital malformation syndromes affecting multiple systems

MESH PheWeb

Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 Q87

Cause of death: ICD-10 Q87

380

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

380

Check minimum number of events None

380

Include endpoints None

380

Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 Q8

Name in latin Alia syndromata malformationum congenitarum specificata, systemata multa afficientia

Similar endpoints

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List of similar endpoints to Other specified congenital malformation syndromes affecting multiple systems based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Congenital malformation syndromes predominantly affecting facial appearance

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

360

190

170

Unadjusted prevalence (%)

0.12

0.11

0.13

Mean age at first event (years)

24.84

25.31

24.32

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.11	9.61 [3.64, 25.41]	5.0e-6	11
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS – Other specified congenital malformation syndromes affecting multiple systems
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other specified congenital malformation syndromes affecting multiple systems
after Other specified congenital malformation syndromes affecting multiple systems

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Table

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Drugs most likely to be purchased after Other specified congenital malformation syndromes affecting multiple systems

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