Congenital malformations of the nervous system

DOID MESH PheWeb

Q17_CONGEN_MALFO_NERVOUS_SYSTEM

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 Q00-Q07

Cause of death: ICD-10 Q00-Q07

394

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

394

Check minimum number of events None

394

Include endpoints

Q17_ANENC_SIMIL_MALFO

Q17_ENCEPHALOCELE

Q17_MICROCEPHALY

Q17_CONGEN_HYDROCEPHALUS

Q17_OTHER_CONGEN_MALFO_BRAIN

Q17_SPINA_BIFIDA

Q17_OTHER_CONGEN_MALFO_SPINAL_CORD

Q17_OTHER_CONGEN_MALFO_NERVOUS_SYSTEM

430

Q17_CONGEN_MALFO_NERVOUS_SYSTEM

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF4

Parent code in ICD-10 Q

Name in latin Malformationes congenitae systematis nervosi

Similar endpoints

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List of similar endpoints to Congenital malformations of the nervous system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	409	276	133
Unadjusted prevalence (%)	0.13	0.16	0.10
Mean age at first event (years)	28.53	30.04	25.39

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.21 [0.89, 5.49]	8.8e-2	13
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_CONGEN_MALFO_NERVOUS_SYSTEM – Congenital malformations of the nervous system
GWS hits: 0

Survival analyses between endpoints

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Plot

before Congenital malformations of the nervous system
after Congenital malformations of the nervous system

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Table

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Drugs most likely to be purchased after Congenital malformations of the nervous system

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