Urolithiasis

N14_UROLITHIASIS

nephrolithiasis: The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 N20-N23
Cause of death: ICD-10 N20-N23

6580

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

6580

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Check minimum number of events None

6580

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N14_UROLITHIASIS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 8060 2672 5388
Unadjusted prevalence (%) 2.61 1.54 3.99
Mean age at first event (years) 51.07 46.14 53.52

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.98 [0.79, 1.22] 8.4e-1 1009
15 years 0.00 0.68 [0.56, 0.83] 1.1e-4 459
5 years 0.00 1.20 [0.99, 1.47] 6.5e-2 206
1 year 0.00 2.13 [1.61, 2.84] 1.8e-7 67

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_UROLITHIASIS – Urolithiasis
GWS hits: 13

Survival analyses between endpoints

Plot

before Urolithiasis
after Urolithiasis

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