Calculus of kidney and ureter

N14_CALCUKIDUR

nephrolithiasis: The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 N20

Hospital discharge: ICD-9 592

Hospital discharge: ICD-8 592

Cause of death: ICD-10 N20

Cause of death: ICD-9 592

Cause of death: ICD-8 592

7836

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7836

Check minimum number of events None

7836

Include endpoints None

7836

N14_CALCUKIDUR

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 N20-N23

Name in latin Nephrolithiasis et/sive ureterolithiasis

Similar endpoints

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List of similar endpoints to Calculus of kidney and ureter based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7433	2558	4875
Unadjusted prevalence (%)	2.41	1.47	3.61
Mean age at first event (years)	50.16	45.93	52.37

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.97 [0.75, 1.26]	8.5e-1	884
15 years	0.00	0.70 [0.56, 0.87]	1.7e-3	404
5 years	0.00	1.22 [0.98, 1.52]	7.5e-2	168
1 year	0.00	2.02 [1.46, 2.79]	2.5e-5	50

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_CALCUKIDUR – Calculus of kidney and ureter
GWS hits: 11

Survival analyses between endpoints

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Plot

before Calculus of kidney and ureter
after Calculus of kidney and ureter

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Table

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Drugs most likely to be purchased after Calculus of kidney and ureter

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