Renal failure

N14_RENFAIL

kidney failure: An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector

Filter registries None

0

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
N14_RENFAIL

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 10060 3490 6570
Unadjusted prevalence (%) 3.26 2.01 4.87
Mean age at first event (years) 66.19 64.72 66.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 10.26 [8.30, 12.68] <1e-100 3056
15 years 0.01 2.18 [1.75, 2.70] 2.0e-12 511
5 years 0.01 7.84 [6.78, 9.07] <1e-100 1022
1 year 0.01 37.83 [33.13, 43.21] <1e-100 1490

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_RENFAIL – Renal failure
GWS hits: 3

Survival analyses between endpoints

Plot

before Renal failure
after Renal failure

loading spinner Loading survival analyses plot