Migraine, single triptan purchase ok & required. ICD-code if available is included

MIGRAINE_TRIPTAN

migraine disorder: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

TRIPTAN1

31789

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

31789

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MIGRAINE_TRIPTAN

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 30667 25585 5082
Unadjusted prevalence (%) 9.94 14.74 3.76
Mean age at first event (years) 37.78 37.22 40.63

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.99 [0.78, 1.26] 9.4e-1 404
15 years 0.00 0.81 [0.64, 1.02] 7.9e-2 196
5 years 0.00 1.09 [0.80, 1.48] 6.0e-1 56
1 year 0.00 1.54 [0.88, 2.68] 1.3e-1 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: MIGRAINE_TRIPTAN – Migraine, single triptan purchase ok & required. ICD-code if available is included
GWS hits: 9

Survival analyses between endpoints

Plot

before Migraine, single triptan purchase ok & required. ICD-code if available is included
after Migraine, single triptan purchase ok & required. ICD-code if available is included

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Migraine, single triptan purchase ok & required. ICD-code if available is included