Other/unspecified synovitis and tenosynovitis

M13_TENDOSYNOVITISNAS

Tenosynovitis: Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M65.8, M65.9

Hospital discharge: ICD-9 7270

Hospital discharge: ICD-8 7310[0-3]

Hospital discharge: excluded ICD-9 7270A

Cause of death: ICD-10 M65.8, M65.9

Cause of death: ICD-9 7270

Cause of death: ICD-8 7310[0-3]

Cause of death: excluded ICD-9 7270A

2945

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2938

Check minimum number of events None

2938

Include endpoints None

2938

M13_TENDOSYNOVITISNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Other/unspecified synovitis and tenosynovitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2851	1786	1065
Unadjusted prevalence (%)	0.92	1.03	0.79
Mean age at first event (years)	42.74	42.83	42.58

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.83 [0.53, 1.30]	4.1e-1	196
15 years	0.00	0.58 [0.38, 0.88]	1.1e-2	79
5 years	0.00	0.91 [0.57, 1.48]	7.1e-1	30
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_TENDOSYNOVITISNAS – Other/unspecified synovitis and tenosynovitis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other/unspecified synovitis and tenosynovitis
after Other/unspecified synovitis and tenosynovitis

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Table

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Drugs most likely to be purchased after Other/unspecified synovitis and tenosynovitis

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