Myalgia

M13_MYALGIA

fibromyalgia: A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M79.1
Hospital discharge: ICD-9 7291
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M79.1
Cause of death: ICD-9 7291
Cause of death: ICD-8 $!$

5231

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5218

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Check minimum number of events None

5218

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Include endpoints None

5218

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M13_MYALGIA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M79
Name in latin Myalgia

Summary Statistics

Key figures

All Female Male
Number of individuals 5020 3563 1457
Unadjusted prevalence (%) 1.63 2.05 1.08
Mean age at first event (years) 52.40 50.82 56.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.67 [1.05, 2.66] 3.0e-2 185
15 years 0.00 0.82 [0.54, 1.23] 3.3e-1 73
5 years 0.00 2.29 [1.62, 3.24] 2.6e-6 71
1 year 0.00 4.39 [2.79, 6.93] 1.8e-10 27

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_MYALGIA – Myalgia
GWS hits: 1

Survival analyses between endpoints

Plot

before Myalgia
after Myalgia

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